Prolactin as a Marker of Active Disease in Systemic Lupus Erythematosus

Objetives. To determine the correlation between prolactin levels and disease activity classified based on Mexican lupus erythematosus systemic index (MEX SLEDAI). Methods. In this cross-sectional observational study, serum prolactin, age, sex, treatment, as well manifestations of active were determined. Disease was evaluated using Systemic Lupus Erythematosus Activity Index (MEX-SLEDAI). The MEX-SLEDAI with determined Spearman coefficient. significance differences continuous variables non-paired Student’s t test categorical Chi-square test. Results. 55 patients included, 10 (18.1%) had ≥7 45 (81.8%) less than 7. A positive found a rho 0.387 (p = 0.004) prolactin. Subjects hyperprolactinemia 80% at renal level 0.001). Conclusion. There is significant activity. Hyperprolactinemia detected in those ≥7.